Today the future is here
 Welcome to Histos 5, the rapid microwave histoprocessor for same-day diagnosis for reduced patient stress and improved patient care.
The Histos 5 is the result of Milestone’s 18 years of research in applying microwaves to histoprocessing and of the experience of hundreds of microwave histoprocessors installed worldwide. The Histos 5 provides the ideal combination of processing performance, reagent efficiency, and environmental sensitivity, without sacrifying the morphology and quality histopathologists expect.
The growing research in the application of microwaves for the acceleration of tissue processing has been fuelled by the need for dramatic reduction in tissue processing times. The new Histos 5 is the latest result of Milestone’s commitment to innovation.
The Histos 5, which combines microwave irradiation with state-of-the-art computer control of power, time and temperature, consistently produces rapidly processed tissues with optimal cytomorphology and improved tissue sectioning properties.
The Histos 5 unique processing technique provides higher throughput, same-day processing for same-day diagnosis, less patient stress, and a greener and safer work environment. Rapid and consistent processing of specimens of 4-5 mm thickness is made possible by the patented intermediate evaporation step with a preset vacuum protocol down to 100 mbar.
Same-day diagnosis: benefits for the patient and the patient care management team
 For the Grossing Room Operator
- Carry out grossing according to standard procedures
 For the Histologist
- Improved workload distribution: process as required for a more even workload distribution
- Flexibility: process 4-55-110 cassettes
- Easy sectioning
 For the Pathologist
- Histos 3/5 processed slides enable the pathologist to deliver same-day diagnosis of slides
- Same-day diagnosis will enhance the pathologist’s role in cancer patient management
 For the Lab Administrator
- Improved work environment for laboratory personnel
- Reduced cost for reagents storage and disposal
 For the Oncologist and Clinician
- Within hours oncologists & clinicians can advise patients on the base of definitive diagnosis
- Treatment can be initiated immediately
 For the Hospital Administrator
- Reduced patient anxiety and stress by providing results within hours
- Dramatic improvements in efficiency and laboratory productivity
 For the Patient
- Elimination of needless anguish
- More timely start of needed treatment
Histos 5: the Breakthrough
Histoprocessing
Conventional: Overnight processing using 12-14 reagents. Diagnosis after 48-72 hours using hazardous reagents: xylene and formalin.
Histos 5: Same-day processing and diagnosis using 2-3 reagents only with low toxicity: FineFix, ethanol, isopropanol, JFC, ProWave.
Decalcification
Conventional: hours.
Histos 5: Minutes: decalcification plus histoprocessing of bone marrow biopsies in 240 minutes.
Special Stains
Conventional: GMS (fungi) in 130' - Masson trichrome in 120' - Alcian blue in 23' - Grimelius (agyrophil) in 65'.
Histos 5: GMS (fungi) in 25' - Masson trichrome in 32' - Alcian blue in 13' - Grimelius (agyrophil) in 13'.
Gross Hardening
Conventional: 24 hours.
Histos 5: 45/60 minutes.
Fixation
Conventional: Hours.
Histos 5: Minutes.
Epitope Retrieval
Conventional: Manual.
Histos 5: Walk-away, automatic documented protocols.
High processing flexibility and simplicity
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| Authorized user log-in |
Select the maximum thickness of specimen to be processed |
Select maximum number of cassettes (55-110) |
Select reagents to be used Ethanol/Isopropanol/ProWave/JFC |
Press "Start" and the unit runs automatically tracing the ramping and time at temperature (T.A.T) protocol |
Press "Go to Wax" and impregnation step will begin and run unattended. |
Tap on the screen to start simultaneously the next run with the dehydration/clearing step. |
Microwave technology
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