KOS
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The microwave multifunctional tissue processor you were waiting for

A state-of-the-art, multifunctional microwave tissue processor, the KOS is ideally suited as a complement to existing capabilities found in histology laboratories, where the multitasking nature of the instrument can enhance and accelerate many of the typical applications encountered.

Smart. Icons driven.
Fast. Factory prestored optimized, full documented protocols for rapid, microwave enhanced procedures. No calibrations required. Just plug-in and process.
Reliable. Sensors controlled for protection of your precious specimens.
Flexible. User defined customized programs can be created and added to a most used favorites list for quick access, as required for meeting the needs of each user laboratory.

Multifunctional unit

Rapid tissue processing
Same day results for all tissue types
  • From 1 to 45 cassettes
  • Ideal for transplant centers (Urgent biopsies)
  • Safe. No xylene
  • No proprietary reagents (Ethanol – isopropanol only)
High quality slides

No compromise in regard to morphology and staining expression. Staining properties of microwave processed specimens are excellent for H&E routine staining, HC, IHC, FISH. In a fraction of the time.

Adenocarcinoma, microwave processed Cytokeratin CAM5.2, x 400 Breast cells HER2 amplification detection by IHC, processed by microwaves. Hematoxylin counterstain, x 400 Breast cellsHER2 amplification detection by FISH processed by microwaves. Red-labeled HER2 probe, x 800 Colonic biopsy, microwave processed in 30 minutes. H&E, x 400
Adenocarcinoma, microwave processed Cytokeratin CAM5.2, x 400. Breast cells HER2 amplification detection by IHC, processed by microwaves. Hematoxylin counterstain, x 400. Breast cellsHER2 amplification detection by FISH processed by microwaves. Red-labeled HER2 probe, x 800. Colonic biopsy, microwave processed in 30 minutes. H&E, x 400.
 
Fast. Unmatched tissue processing times
  • 30 minutes... for transplant biopsies including fixation.
  • 30 minutes... for 1.5 mm biopsies. Add 10 minutes to include fixation.
  • 80 minutes... for 3 mm biopsies. Add 25 minutes to include fixation.
Easy. Icons driven menù
1. Select thickness 2. Select n° of cassettes 3. Select reagents 4. Press "GO" 5. Press "START" 6. Time left displayed
1. Select thickness 2. Select n° of cassettes 3. Select reagents 4. Press "GO" 5. Press "START" 6. Time left displayed
Bone Marrow processing
Same-day diagnosis for bone marrow trephine biopsies. Will this help your patient?

Decalcification + Processing in less than 3 hours!
An ideal application of the technology and multifunctionality of the KOS
Optimized decalcification and processing protocols are factory stored.

EDTA
Decalcification 80 minutes + Processing 60 minutes = Total time 140 minutes

Formic acid (5%)
Decalcification 20 minutes + Processing 60 minutes = Total time 80 minutes

Fast turn around time
    Minutes Temp. °C  
Fast turn around time Fixation in formalin 10 50 Bone marrow, EDTA, H&E x 100
Rinsing in tap water 10  
Decalcification (formic acid) 20 50
Rinsing in ethanol 2  
Tissue processing (Prowave) 15  
Impregnation in Wax 23  
Total time (minutes) 80  
Rapid Bone Decalcification
Up to 45 cassettes: hours, not days!

An excellent application for the KOS.
The efficient stirring continuously keeps the bone surface in contact with “fresh” decalcifier, positively influencing the equilibrium:

Equilibrium

Simply select the temperature, the number of cassettes and the decalcifying solution: then press "GO".

Examples of core biopsy decalcification times (50 °C)

Core biopsy decalcification times

Special Stains
Up to 76% time saving for histochemical staining protocols

Several time consuming staining procedures are enhanced by microwave irradiation.
Factory stored, optimized, step by step protocols for most common stains for 1-40 slides.
Preset or customized programs guarantee operator independent, consistent results.

  • No splashing, constant pH conditions
  • Magnetic stiring for temperature uniformity along the entire length of the slides
Stains
Stains Standard (min) KOS (min) Time Saving (%) Staining intensity
GMS (Fungi) 130 25 76 Increased
GRIMELIUS (Agryrophil) 65 13 72 Increased
MASSON TRICHROME 120 32 70 Increased
MASSON FONTANA 80 19 70 Increased
PAS 50 21 50 Increased
ALCIAN BLUE 34 13 61 Increased
ZIEHL NIELSEN 39 11 61 Increased
ELASTICA (ORCEIN) 30 7 62 Increased
PEARLS IRON STAIN 21 8 46 Increased

 

1. Select stains menu 2. Select specific stain 3. Follow the screen indications 4. MW programs are pre-stored
1. Select stains menu 2. Select specific stain 3. Follow the screen indications 4. MW programs are pre-stored

 
Alcian Blue: Bowel biopsy, x 400 Grimelius Argyrophyl cells in Duodenum, x 400 PAS, stomach gland, x 400
Alcian Blue: Bowel biopsy, x 400. Grimelius Argyrophyl cells in Duodenum, x 400. PAS, stomach gland, x 400.
Antigen retrieval
Time at temperature steps
Time at temperature steps

 
  1. Select temperature
  2. Select histomodule
  3. Select time
  4. Press "GO"

User’s programs can be easily set up and stored under “Favorites” for easy operation.

 

Microwave and sensor technology

Microwave and sensor technology


Kos is available in 3 beautiful....sorry, stainful colors to suit the atmosphere of your laboratory!

3 beautiful colors!