FlashFREEZE

The science of flash freezing
for standardized tissue banking

FlashFREEZE

The science of flash freezing for standardized tissue banking

The problem

Start with a good preparation

There are few resources as valuable to cancer researchers as tissue samples, the biospecimens that patients donate to aid in the search for cancer-related biomarkers. Harvesting and storing human tissue for research purposes is not new. However, it has become clear that the great majority of biospecimens stored in the world’s biorepositories may not be suited for the state-of-the-art genomics, proteomics, metabolomics, and the other bioanalytical technologies used today to search for cancerrelated biomarkers. The irreproducibility of many reported biomarkers is due at least in part, to the fact that the biospecimens utilized are often procured using different collection, processing and storage techniques.*
Such variability can lead to significant differences in biospecimen molecular integrity.

* International Approaches to Advancing Biospecimen Science. Helen M. More et all. Cancer Epidemiol Biomarkers Prev. May 2011; 20(5): 729-732

The solution

The solution

To overcome some of these difficulties Milestone has developed the FlashFREEZE unit to standardize the biospecimen flash freezing processing step of biospecimen.
With FlashFREEZE it is now possible to run evidence-based biospecimen freezing protocols with the full documentation needed for QA purposes. FlashFREEZE combines the advantages of a state-of-the-art Stirling cooler, capable of reaching temperatures down to -80°C. FlashFREEZE eliminates the need of toxic reagents such as isopentane.

THE UNIQUE FEATURES OF FLASHFREEZE

  • High flexibility: Standardized freezing at -80°C for all tissue types
  • Fast: 1 hour 40 minutes to the final operating temperature of -80°C. Biospecimens are frozen in only 60-120 seconds
  • Safe: HEPA cap filter
  • Environmentally friendly: No standard compressor, no CFC
  • Fully documented

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Simple and intuitive operations make everyone an expert


Step 1

Step 1

Open the properly identified cryovial
Step 2

Step 2

Place the biospecimen inside
Step 3

Step 3

Close the cryovial
Step 4

Step 4

Place the cryovial in the freezing fluid
Step 5

Step 5

Place the special tool over the cryovial...
Step 6

Step 6

... To avoid floating
Step 7

Step 7

Close the cover and start timer
Step 8

Step 8

After time is expired, open the cover and extract the cryovial with the frozen specimen
Step 9

Step 9

The cryovial can now be placed in the holder for storage

Video

Watch our video to discover our product in action! Unique design, outstanding quality and technology innovation are key features.

Catalog

Take a moment to consult our catalog to learn all the advantages of Milestone cutting-edge FlashFREEZE unit.

FlashFREEZE
Milestone Biobanking Processing

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